LP-533401 hydrochloride( —— )

Catalog No. M33410 CAS No. 1040526-12-2

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

LP-533401 hydrochloride
Note

Research use only, not for human use.
Brief Description

LP-533401 hydrochloride is a peripheral Tph inhibitor that cannot cross the blood-brain barrier that inhibits 5-hydroxytryptamine synthesis and can be used to study periodontal disease and hepatic steatosis.
Description

LP-533401 hydrochloride is a tryptophan hydroxylase 1 inhibitor that regulates serotonin production in the gut.
In Vitro

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In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

——
Indication

——

CAS Number

1040526-12-2
Formula Weight

562.94
Molecular Formula

C27H23ClF4N4O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 25 mg/mL (44.41 mM; Ultrasonic )
SMILES

Cl.N[C@@H](Cc1ccc(cc1)-c1cc(OC(c2ccc(cc2)-c2cccc(F)c2)C(F)(F)F)nc(N)n1)C(O)=O
Chemical Name

——

1. Yadav, V.K., et al. Inhibition of gut-derived serotonin synthesis: A potential bone anabolic treatment. Nat. Med. 16(3), 308-312 (2010).

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